Search
Close this search box.

PNAClamp™ Mutation Detection Kit IDH2

For the detection of IDH2 mutations in tissue biopsies

Cat. No. PNAC-5101

PNAClamp™ Mutation Detection Kit IDH2

IDH2 is frequently mutated in glioma, acute myeloid leukemia and myelodysplastic syndromes. Mutations generally involve point mutations at residues R140 and R172 of the protein. Mutations in IDH1 and IDH2 result in a detrimental “gain of function”: instead of converting isocitrate to α-ketoglutarate, mutated IDH1 or IDH2 converts isocitrate to 2-hydroxyglutarate. 2-hydroxyglutarate inhibits other proteins involved in epigenetic regulation.

Technical Data

Yes

Marca

Other products

Biospin FFPE Tissue RNA Extraction Kit-50T-PCR/RT-PCR(BSC66S1)
This kit is used to extract high purity RNA from...
Bactotype Mastitis Env PCR Kit (96 reactions)
For DNA identification of Escherichia coli , Klebsiella , Streptococcus...
2X Q-PCR Master Mix (TaqMan, ROX) – TQ2110
ExcelTaq ™ 2X Q-PCR Master Mix (TaqMan, ROX) is a...
Gentier 96 R – Real Time PCR – Thermal Cycler
Gentier's real-time PCR system is designed to perform a fast...
Scroll to Top
Abrir chat
1
¡Hola!
¡Este PNAClamp™ Mutation Detection Kit IDH2 puede ser tuyo solo por $ 0!
Si tienes alguna duda, pregúntanos.